The Frenchman missed the midweek Capital One Cup win over rivals Tottenham, and will sit out once again against the Foxes.
Fellow midfielder Santi Cazorla returns from a one-match suspension after his red card at Chelsea but defender Gabriel must await the outcome of an appeal against his Football Association charge of improper conduct at Stamford Bridge, which could see him suspended.
Jack Wilshere has had an operation on a hairline fracture in his left fibula, while forward
Danny Welbeck and Czech midfielder Tomas Rosicky (both knee) are also sidelined.


Arsenal midfielder Santi Cazorla

Claudio Ranieri is expected to make wholesale changes after the midweek cup win over West Ham.
Kasper Schmeichel, Ritchie De Laet, Wes Morgan, Danny Drinkwater, Ngolo Kante, Riyad Mahrez and Jamie Vardy are all likely to return to the starting line up, but on-loan winger Nathan Dyer (knee) remains out injured.